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Article Reference A prospective, observational, epidemiological evaluation of the aetiology and antimicrobial susceptibility of acute otitis media in Saudi children younger than 5years of age.
Information regarding acute otitis media (AOM) aetiology is important for developing effective vaccines. Here, bacterial aetiology and antimicrobial ...
Article Reference Tympanic membrane changes in experimental acute otitis media and myringotomy.
The present experimental study explored pathomorphological changes and calcium depositions in the tympanic membrane during experimental acute otitis media ...
Article Reference Otomicroscopic findings and systemic interleukin-6 levels in relation to etiologic agent during experimental acute otitis media.
The aim of the present study was to explore whether it was possible to differentiate the clinical course and the otomicroscopic appearance of acute otitis ...
Article Reference Development of myringosclerosis during acute otitis media caused by Streptococcus pneumoniae and non-typeable Haemophilus influenzae: a clinical otomicroscopical study using the rat model.
The present study was performed in order to study development of myringosclerosis during acute otitis media caused by different bacteria in myringotomized and ...
Article Reference Calcium deposition and expression of bone modelling markers in the tympanic membrane following acute otitis media.
In accordance with clinical findings, myringosclerosis develops after otitis media (OM) and paracentesis in an experimental setting. The pathogenesis of this ...
Article Reference Passive transfer of antiserum specific for immunogens derived from a nontypeable Haemophilus influenzae adhesin and lipoprotein D prevents otitis media after heterologous challenge.
We recently determined that passive transfer of serum directed against a synthetic peptide called LB1 or a recombinant fusion protein immunogen ...
Article Reference Protection against development of otitis media induced by nontypeable Haemophilus influenzae by both active and passive immunization in a chinchilla model of virus-bacterium superinfection.
Three separate studies, two involving active-immunization regimens and one involving a passive-transfer protocol, were conducted to initially screen and ...
Article Reference Changes in mucosal goblet cell density in acute otitis media caused by non-typeable Haemophilus influenzae.
The correlation between secretory otitis media and increased goblet cell density in the middle ear mucosa is well established. Previous studies have shown that ...
Article Reference Increased secretory capacity of the middle ear mucosa after acute otitis media caused by Haemophilus influenzae type B.
Secretory otitis media is associated with a highly increased goblet cell density of the middle ear mucosa. Previous studies have shown that a single episode of ...
Article Reference The tympanic membrane and middle ear mucosa during non-typeable Haemophilus influenzae and Haemophilus influenzae type b acute otitis media: a study in the rat.
Non-typeable Haemophilus influenzae (NTHi) and encapsulated Haemophilus influenzae type b (Hib) were inoculated into the middle ears of Sprague-Dawley rats. ...
Article Reference Peptidoglycan isolated from nontypeable Haemophilus influenzae induces experimental otitis media in the chinchilla.
Bacterial cell wall components induce a number of biologic effects and promote inflammatory changes in a variety of hosts. Peptidoglycan isolated from ...