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Article Reference Haemophilus influenzae uses the surface protein E to acquire human plasminogen and to evade innate immunity.
Pathogenic microbes acquire the human plasma protein plasminogen to their surface. In this article, we characterize binding of this important coagulation ...
Article Reference Peptidylarginine deiminases present in the airways during tobacco smoking and inflammation can citrullinate the host defense peptide LL-37, resulting in altered activities.
Bacterial colonization of the lower respiratory tract is frequently seen in chronic obstructive pulmonary disease (COPD), and may cause exacerbations leading ...
Article Reference Human neutrophil elastase degrades SPLUNC1 and impairs airway epithelial defense against bacteria.
Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are a significant cause of mortality of COPD patients, and pose a huge burden on ...