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Article Reference T helper 17 cells play a critical pathogenic role in lung cancer.
Lung cancer development is associated with extensive pulmonary inflammation. In addition, the linkage between chronic obstructive pulmonary disease (COPD) and ...
Article Reference Collaborative studies in mucosal immunology in Goroka.
A collaborative program between the Papua New Guinea (PNG) Institute of Medical Research and the Hunter Mucosal Group has completed studies relevant to ...
Article Reference Anti-inflammatory IgG production requires functional P1 promoter in β-galactoside α2,6-sialyltransferase 1 (ST6Gal-1) gene.
The anti-inflammatory properties associated with intravenous immunoglobulin therapy require the sialic acid modification of the N-glycan of the Fc domain of ...
Article Reference Interleukin 6, but not T helper 2 cytokines, promotes lung carcinogenesis.
Several epidemiologic studies have found that smokers with chronic obstructive pulmonary disease (COPD), an inflammatory disease of the lung, have an increased ...
Article Reference Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model.
Lung cancer is the leading cause of cancer deaths in the United States. In addition to genetic abnormalities induced by cigarette smoke, several epidemiologic ...
Article Reference Serotypes and pathogens in paediatric pneumonia.
Multiple pathogens may cause pneumonia. Three vaccines with demonstrated or potentially major impact on paediatric pneumonia caused by pneumococcus and/or ...
Article Reference The relationship between undernutrition and humoral immune status in children with pneumonia in Papua New Guinea.
Malnutrition is a significant risk factor for childhood infectious diseases in developing countries, including Papua New Guinea (PNG). Whilst the mechanisms ...
Article Reference Bacteria-mucin interaction in the upper aerodigestive tract shows striking heterogeneity: implications in otitis media, rhinosinusitis, and pneumonia.
The mucociliary system of the upper and lower respiratory tracts is a critical nonspecific pathway for the elimination of bacteria and other particulate ...
Article Reference Mixed infection is common in children with respiratory adenovirus infection.
The presence of concomitant viral or bacterial infection was evaluated in 20 patients hospitalized for adenovirus infection of the middle or lower airways by ...
Article Reference A rat model of prolonged pulmonary infection due to nontypable Haemophilus influenzae.
Pulmonary colonization and infection with nontypable (unencapsulated) Haemophilus influenzae (NTHI) occurs commonly in the setting of chronic lung diseases. ...
Article Reference Effect of primary immunization on pulmonary clearance of nontypable Haemophilus influenzae.
Nontypable Haemophilus influenzae (NTHI) is being increasingly recognized as a cause of both adult pneumonia and acute infectious exacerbations in chronic ...
Article Reference Nontypable Haemophilus influenzae nosocomial pulmonary infections in children following intubation.
Twenty-nine intubated pediatric patients were prospectively studied to determine whether nontypable Haemophilus influenzae (NTHI) is associated with the ...
Article Reference Emerging pathogens in nosocomial pneumonia.
The organisms responsible for nosocomial pneumonia are continuously evolving. Gram-negative bacilli have become the most common etiologic agents over the past ...
Article Reference Nontypable Haemophilus influenzae: a review of clinical aspects, surface antigens, and the human immune response to infection.
Nontypable Haemophilus influenzae has now become well established as an important pathogen in both adults and children. Recent work has identified clear ...
Article Reference Neonatal sepsis due to nontypable Haemophilus influenzae.
From August 1980 through July 1984, 19 neonates had sepsis due to Haemophilus influenzae. Onset of disease occurred within 48 hours after birth of all the ...
Article Reference Etiology of community-acquired pneumonia in patients requiring hospitalization.
The etiology of community-acquired pneumonia was studied in 127 patients with roentgenologically verified pneumonia who needed hospitalization. Etiology was ...
Article Reference Outer membrane proteins of nontypable Haemophilus influenzae and reactivity of paired sera from infected patients with their homologous isolates.
Normal human serum and acute or convalescent serum from patients infected with nontypable Haemophilus influenzae were tested for reactivity with electroblotted ...
Article Reference Immunoglobulin A from bronchopulmonary secretions blocks bactericidal and opsonizing effects of antibody to nontypable Haemophilus influenzae.
Patients with chronic bronchitis are colonized by and may develop acute bronchopulmonary infection due to nontypable Haemophilus influenzae (NTHI) despite the ...
Article Reference Nontypable Haemophilus influenzae are unencapsulated both in vivo and in vitro.
Some investigators have suggested that nontypable Haemophilus influenzae isolated from sputum of adults with pneumonia are variant forms of typable H ...
Article Reference A fluorescent multiplexed bead-based immunoassay (FMIA) for quantitation of IgG against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis protein antigens.
Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis are pathogens commonly associated with infectious diseases in childhood. This study ...