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Article Reference The multifunctional host defense peptide SPLUNC1 is critical for homeostasis of the mammalian upper airway.
Otitis media (OM) is a highly prevalent pediatric disease caused by normal flora of the nasopharynx that ascend the Eustachian tube and enter the middle ear. ...
Article Reference Profiling LPS glycoforms of non-typeable Haemophilus influenzae by multiple-stage tandem mass spectrometry.
Non-typeable (acapsular) Haemophilus influenzae (NTHi) is a major cause of otitis media accounting for 25-30% of all cases of the disease. Lipopolysaccharide ...
Article Reference Calcium deposition and expression of bone modelling markers in the tympanic membrane following acute otitis media.
In accordance with clinical findings, myringosclerosis develops after otitis media (OM) and paracentesis in an experimental setting. The pathogenesis of this ...
Article Reference Nontypable Haemophilus influenzae are unencapsulated both in vivo and in vitro.
Some investigators have suggested that nontypable Haemophilus influenzae isolated from sputum of adults with pneumonia are variant forms of typable H ...
Article Reference Human neutrophil elastase degrades SPLUNC1 and impairs airway epithelial defense against bacteria.
Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are a significant cause of mortality of COPD patients, and pose a huge burden on ...
Article Reference Selection against glycosylation sites in potential target proteins of the general HMWC N-glycosyltransferase in Haemophilus influenzae.
The HMWABC system of non-typeable Haemophilus influenzae (NTHi) encodes the HMWA adhesin glycoprotein, which is glycosylated by the HMWC glycosyltransferase. ...