You are here: Home Published Research Nontypeable Haemophilus influenzae genetic islands associated with chronic pulmonary infection.

Lixin Zhang, Jingping Xie, Mayuri Patel, Arsala Bakhtyar, Garth D Ehrlich, Azad Ahmed, Josh Earl, Carl F Marrs, Daniel Clemans, Timothy F Murphy, and Janet R Gilsdorf (2012)

Nontypeable Haemophilus influenzae genetic islands associated with chronic pulmonary infection.

PloS one, 7(9):e44730.

Haemophilus influenzae (Hi) colonizes the human respiratory tract and is an important pathogen associated with chronic obstructive pulmonary disease (COPD). Bacterial factors that interact with the human host may be important in the pathogenesis of COPD. These factors, however, have not been well defined. The overall goal of this study was to identify bacterial genetic elements with increased prevalence among H. influenzae strains isolated from patients with COPD compared to those isolated from the pharynges of healthy individuals.

Blotting, Southern, Case-Control Studies, Chronic Disease, Genes, Bacterial, Genetic Predisposition to Disease, Haemophilus influenzae, Humans, Open Reading Frames, Polymerase Chain Reaction, Pulmonary Disease, Chronic Obstructive, Virulence
Blotting, Southern, Case-Control Studies, Chronic Disease, Genes, Bacterial, Genetic Predisposition to Disease, Haemophilus influenzae, Humans, Open Reading Frames, Polymerase Chain Reaction, Pulmonary Disease, Chronic Obstructive, Virulence
 
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