You are here: Home Published Research Non typable-Haemophilus influenzae biofilm formation and acute otitis media.

Assaf Mizrahi, Robert Cohen, Emmanuelle Varon, Stephane Bonacorsi, Stephane Bechet, Claire Poyart, Corinne Levy, and Josette Raymond (2014)

Non typable-Haemophilus influenzae biofilm formation and acute otitis media.

BMC infectious diseases, 14(1):400.

Non-typable Haemophilus influenzae (NT-Hi) infection is frequently associated with acute otitis media (AOM) treatment failure, recurrence or chronic otitis media. Persistence of otopathogens in a biofilm-structured community was implicated in these situations. Here, we compared biofilm production by H. influenzae strains obtained by culture of middle ear fluid (MEF) from children with AOM treatment failure and by strains isolated from nasopharyngeal (NP) samples from healthy children or those with AOM (first episode or recurrence). We aimed to evaluate an association of clinical signs and in vitro biofilm formation and establish risk factors of carrying a biofilm-producing strain.

Acute Disease, Biofilms, Child, Preschool, Haemophilus influenzae, Humans, Infant, Multivariate Analysis, Nasopharynx, Otitis Media, Recurrence, Risk Factors, Streptococcus pneumoniae, Treatment Failure
Acute Disease, Biofilms, Child, Preschool, Haemophilus influenzae, Humans, Infant, Multivariate Analysis, Nasopharynx, Otitis Media, Recurrence, Risk Factors, Streptococcus pneumoniae, Treatment Failure
 
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