You are here: Home Published Research Otitis media: prospects for prevention.

Mark Haggard (2008)

Otitis media: prospects for prevention.

Vaccine, 26 Suppl 7:G20–G24.

Alternatives to vaccination for preventing the considerable morbidity of otitis media (OM) are limited. Non-typable Haemophilus influenzae (NTHi) and Streptococcus pneumoniae together account for approximately 80% of OM cases worldwide, so vaccines against these most serious pathogens should materially reduce the burden of OM. Early trial data for a vaccine prototype including NTHi and 11 pneumococcal serotypes, interpreted carefully in relation to other trials, suggest that OM can now be considered a vaccine-preventable disease. Despite differences of scenario according to healthcare and bacteriology circumstances of different countries, a provisional analysis of health-economic precedents and policy considerations favours vaccination.

Bacterial Vaccines, Child, Preschool, Clinical Trials as Topic, Haemophilus Infections, Haemophilus Vaccines, Haemophilus influenzae, Humans, Infant, Otitis Media, Pneumococcal Infections, Pneumococcal Vaccines, Streptococcus pneumoniae, Treatment Outcome
Bacterial Vaccines, Child, Preschool, Clinical Trials as Topic, Haemophilus Infections, Haemophilus Vaccines, Haemophilus influenzae, Humans, Infant, Otitis Media, Pneumococcal Infections, Pneumococcal Vaccines, Streptococcus pneumoniae, Treatment Outcome
 
Document Actions