You are here: Home Published Research The TGF-beta-pseudoreceptor BAMBI is strongly expressed in COPD lungs and regulated by nontypeable Haemophilus influenzae.

Daniel Drömann, Jan Rupp, Kristina Rohmann, Sinia Osbahr, Artur J Ulmer, Sebastian Marwitz, Kristina Röschmann, Mahdi Abdullah, Holger Schultz, Ekkehard Vollmer, Peter Zabel, Klaus Dalhoff, and Torsten Goldmann (2010)

The TGF-beta-pseudoreceptor BAMBI is strongly expressed in COPD lungs and regulated by nontypeable Haemophilus influenzae.

Respiratory research, 11:67.

Nontypeable Haemophilus influenzae (NTHI) may play a role as an infectious trigger in the pathogenesis of chronic obstructive pulmonary disease (COPD). Few data are available regarding the influence of acute and persistent infection on tissue remodelling and repair factors such as transforming growth factor (TGF)-beta.

Case-Control Studies, Enzyme-Linked Immunosorbent Assay, Female, Gene Expression Profiling, Haemophilus influenzae, Humans, Immunohistochemistry, In Situ Hybridization, Inflammation Mediators, Interleukin-8, Lung, Male, Membrane Proteins, Middle Aged, Polymerase Chain Reaction, Pulmonary Disease, Chronic Obstructive, Receptors, Transforming Growth Factor beta, Smad3 Protein, Tissue Culture Techniques, Transforming Growth Factor beta, Tumor Necrosis Factor-alpha
Case-Control Studies, Enzyme-Linked Immunosorbent Assay, Female, Gene Expression Profiling, Haemophilus influenzae, Humans, Immunohistochemistry, In Situ Hybridization, Inflammation Mediators, Interleukin-8, Lung, Male, Membrane Proteins, Middle Aged, Polymerase Chain Reaction, Pulmonary Disease, Chronic Obstructive, Receptors, Transforming Growth Factor beta, Smad3 Protein, Tissue Culture Techniques, Transforming Growth Factor beta, Tumor Necrosis Factor-alpha
 
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